GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs60843830 | 1 | rs60484953 | chr2:221560 | SH3YL1 | chr2:218138-264810:- | -0.93 | -25.81 | 1.24E-92 | Spherical equivalent (joint main effects and education interaction) |
| THCA | cis | rs7267979 | 1 | rs6050542 | chr20:25318879 | ENTPD6 | chr20:25176339-25207360:+ | 0.31 | 6.94 | 1.24E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050542 | chr20:25318879 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.4 | 0.000741 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050542 | chr20:25318879 | FAM182B | chr20:25744102-25848786:- | -0.27 | -5.62 | 3.21E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050542 | chr20:25318879 | NINL | chr20:25433338-25566153:- | 0.35 | 7.18 | 2.68E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050542 | chr20:25318879 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.05 | 5.93E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050544 | chr20:25320228 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.79 | 3.43E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050544 | chr20:25320228 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.44 | 0.000633 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050544 | chr20:25320228 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.47 | 7.25E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050544 | chr20:25320228 | NINL | chr20:25433338-25566153:- | 0.35 | 7.15 | 3.21E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050544 | chr20:25320228 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.68 | 0.000264 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050547 | chr20:25326012 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.79 | 3.36E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050547 | chr20:25326012 | FAM182B | chr20:25744102-25848786:- | -0.27 | -5.64 | 2.97E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050547 | chr20:25326012 | NINL | chr20:25433338-25566153:- | 0.36 | 7.3 | 1.21E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050547 | chr20:25326012 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.02 | 6.84E-5 | Liver enzyme levels (alkaline phosphatase) |